How It Works Mechanism: It mimics natural GHRH, stimulating the pituitary gland to produce and release growth hormone (GH). Downstream Effects: This increases insulin-like growth factor 1 (IGF-1) levels and promotes lipolysis (the breakdown of deep visceral fat surrounding internal organs). Administration: It is administered as a once-daily subcutaneous (under the skin) injection. Uses and Limitations Approved Use: Specifically indicated for reducing excess stomach-area (visceral) fat in HIV-infected patients with lipodystrophy. Not for General Weight Loss: It is not approved or clinically indicated as a general weight-loss or anti-aging drug, though it is sometimes evaluated in broader metabolic and longevity…
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